Dapoxetine (Super P-Force & Priligy)
Clinical guidance, bioequivalence criteria, and verified partner dispensing standards for Dapoxetine (Super P-Force & Priligy). Reviewed by board-certified internal medicine and clinical pharmacotherapy specialists.
Priligy (Dapoxetine) — Dosage Strengths & Online Availability
| Dosage Strength | Pack Supply | Dispensary Price | Stock Status | Verified Order |
|---|---|---|---|---|
| Priligy 30mg | Film-Coated Tablets • 30 / 60 Units | $2.38 / unit | ✓ In Stock (US Dispatch) | Select & Check Price ↗ |
| Priligy 60mg POPULAR | Film-Coated Tablets • 60 / 90 Units (Most Popular) | $1.27 / unitPOPULAR | ✓ In Stock (US Dispatch) | Select & Check Price ↗ |
| Priligy 90mg | Film-Coated Tablets • 90 / 180 Units (Best Value) | $0.45 / unitBEST VALUE | ✓ In Stock (US Dispatch) | Select & Check Price ↗ |
1. Clinical Dosing & Titration Protocols
Daily / Baseline Regimen
Dapoxetine is NOT taken daily. It is strictly an on-demand medication.
On-Demand / Titration Regimen
30mg to 60mg taken with a full glass of water 1 to 2 hours prior to sexual activity.
Contraindicated in severe heart failure, permanent pacemaker, or significant ischemic heart disease.
2. Patient Administration & Safe Usage Guidelines
Always swallow with a full glass of water to minimize dizziness or orthostatic nausea. Do not combine with recreational drugs or excessive alcohol.
Verified Telehealth Access Standards for Dapoxetine (Super P-Force & Priligy)
Our clinical editorial board audits certified partner telehealth dispensaries to guarantee authentic WHO-GMP manufacturing, analytical batch testing, and physician-supervised asynchronous consultation.
Check Telehealth Protocol & Availability ↗3. Frequently Asked Patient Questions
How much does Dapoxetine extend intravaginal ejaculatory latency time (IELT)?
In clinical trials, Dapoxetine 60mg increased IELT by 300% to 400% (from under 1 minute up to 3.5–4.5 minutes), significantly improving ejaculatory control and partner satisfaction.
What is Super P-Force?
Super P-Force is a hybrid formulation combining Sildenafil 100mg (for erectile rigidity) and Dapoxetine 60mg (for ejaculatory control) in a single tablet.
4. Pharmacological Mechanism & Receptor Profile
The only FDA/EMA recognized on-demand short-acting SSRI specifically engineered to delay ejaculatory reflex and extend IELT latency.
Urology & Men's Health • Dapoxetine (Super P-Force & Priligy)
5. Chemical & Human Pharmacokinetic Matrix (Tmax, Half-Life, CYP450)
| Pharmacokinetic Parameter | Clinical Metric | Therapeutic Significance |
|---|---|---|
| Peak Plasma Time (Tmax) | 1.0 to 1.3 hours | Determines latency from ingestion to peak pharmacological onset. |
| Elimination Half-Life (T½) | 1.5 hours (initial rapid clearance; complete elimination within 19h) | Governs duration of action and steady-state dosing intervals. |
| Peak Concentration (Cmax) | 297 ng/mL (60mg) | Maximum observed systemic concentration in human plasma. |
| Bioavailability & Food Interaction | 42% oral bioavailability | Defines oral bioavailability and dietary lipid dependency. |
| Plasma Protein Binding | 99% bound to serum albumin | Governs free circulating drug fraction available for receptor binding. |
| Volume of Distribution (Vd) | 162 Liters | Reflects tissue and lipid compartment penetration. |
| Hepatic Metabolism | Hepatic CYP2D6 and CYP3A4 to inactive desmethyldapoxetine | Primary enzymatic clearance and CYP pathways. |
| Elimination / Excretion | Excreted exclusively in urine as conjugates; negligible fecal elimination | Renal vs biliary/fecal excretion balance. |
6. Drug-Drug Interaction Matrix
| Interacting Agent / Class | Severity Tier | Clinical Mechanism & Management Strategy |
|---|---|---|
| MAO Inhibitors / Serotonergic Agents / Tramadol | Contraindicated | Risk of Serotonin Syndrome. 14-day washout required. |
| CYP3A4 Inhibitors (Ketoconazole) | Major Precaution | Limits dapoxetine clearance. |
7. Adverse Reaction Profile & Clinical Incidence Rates
| Adverse Reaction | Incidence Rate | Physiological Mechanism & Mitigation Strategy |
|---|---|---|
| Nausea | 11% | Transient serotonin 5-HT3 activation in gut. |
| Dizziness | 6% | Vasomotor autonomic response. |
| Headache | 6% | Vasodilatory sensation. |
Peer-Reviewed Scientific Citations & FDA References
- McMahon CG, et al. Efficacy and safety of dapoxetine in men with premature ejaculation. J Sex Med. 2011;8(2):524-539.